Glycogen synthase kinase 3: more than a namesake
…, VK Tulasi, R Sodhi, JA Davis, A Ray - British journal of …, 2009 - Wiley Online Library
Glycogen synthase kinase 3 (GSK3), a constitutively acting multi‐functional serine threonine
kinase is involved in diverse physiological pathways ranging from metabolism, cell cycle, …
kinase is involved in diverse physiological pathways ranging from metabolism, cell cycle, …
[HTML][HTML] Plant secondary metabolites as defense tools against herbivores for sustainable crop protection
…, BA Divekar, R Kumar, BG Gadratagi, A Ray… - International journal of …, 2022 - mdpi.com
Plants have evolved several adaptive strategies through physiological changes in response
to herbivore attacks. Plant secondary metabolites (PSMs) are synthesized to provide …
to herbivore attacks. Plant secondary metabolites (PSMs) are synthesized to provide …
Peptide nucleic acid (PNA): its medical and biotechnical applications and promise for the future
A Ray, B Nordén - The FASEB Journal, 2000 - Wiley Online Library
Synthetic molecules that can bind with high sequence specificity to a chosen target in a
gene sequence are of major interest in medicinal and biotechnological contexts. They show …
gene sequence are of major interest in medicinal and biotechnological contexts. They show …
Evaluating large language models trained on code
We introduce Codex, a GPT language model fine-tuned on publicly available code from
GitHub, and study its Python code-writing capabilities. A distinct production version of Codex …
GitHub, and study its Python code-writing capabilities. A distinct production version of Codex …
Training language models to follow instructions with human feedback
Making language models bigger does not inherently make them better at following a user's
intent. For example, large language models can generate outputs that are untruthful, toxic, or …
intent. For example, large language models can generate outputs that are untruthful, toxic, or …
Associations between end-of-life discussions, patient mental health, medical care near death, and caregiver bereavement adjustment
AA Wright, B Zhang, A Ray, JW Mack, E Trice… - Jama, 2008 - jamanetwork.com
Context Talking about death can be difficult. Without evidence that end-of-life discussions
improve patient outcomes, physicians must balance their desire to honor patient autonomy …
improve patient outcomes, physicians must balance their desire to honor patient autonomy …
Beyond the imitation game: Quantifying and extrapolating the capabilities of language models
…, A Lewkowycz, A Agarwal, A Power, A Ray… - arXiv preprint arXiv …, 2022 - arxiv.org
Language models demonstrate both quantitative improvement and new qualitative
capabilities with increasing scale. Despite their potentially transformative impact, these new …
capabilities with increasing scale. Despite their potentially transformative impact, these new …
Hindsight experience replay
Dealing with sparse rewards is one of the biggest challenges in Reinforcement Learning (RL).
We present a novel technique called Hindsight Experience Replay which allows sample-…
We present a novel technique called Hindsight Experience Replay which allows sample-…
Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses
Emerging viral infections are difficult to control because heterogeneous members periodically
cycle in and out of humans and zoonotic hosts, complicating the development of specific …
cycle in and out of humans and zoonotic hosts, complicating the development of specific …
[HTML][HTML] Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys
The most recent Ebola virus outbreak in West Africa, which was unprecedented in the number
of cases and fatalities, geographic distribution, and number of nations affected, highlights …
of cases and fatalities, geographic distribution, and number of nations affected, highlights …