User profiles for D. Higgins

des higgins

- Verified email at ucd.ie - Cited by 219315

Drew Higgins

- Verified email at mcmaster.ca - Cited by 17294

Multiple sequence alignment with Clustal X

…, JD Thompson, M Gouy, DG Higgins… - Trends in biochemical …, 1998 - cell.com
Figure 1 Screenshot of a session with Clustal X in split-window mode for profile alignment.
Archaeal TFIIB sequences (lower window) are aligned with prealigned eukaryotic TFIIBs (…

Housing and health: time again for public health action

J Krieger, DL Higgins - American journal of public health, 2002 - ajph.aphapublications.org
Poor housing conditions are associated with a wide range of health conditions, including
respiratory infections, asthma, lead poisoning, injuries, and mental health. Addressing housing …

A review on non-precious metal electrocatalysts for PEM fuel cells

Z Chen, D Higgins, A Yu, L Zhang… - Energy & Environmental …, 2011 - pubs.rsc.org
With the approaching commercialization of PEM fuel cell technology, developing active,
inexpensive non-precious metal ORR catalyst materials to replace currently used Pt-based …

Unified Huntington's disease rating scale: reliability and consistency

…, D Abwender, JT Greenamyre, D Higgins… - Movement …, 1996 - iro.uiowa.edu
The Unified Huntington's Disease Rating Scale (UHDRS) was developed as a clinical rating
scale to assess four domains of clinical performance and capacity in HD: motor function, …

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

…, F Plewniak, F Jeanmougin, DG Higgins - Nucleic acids …, 1997 - academic.oup.com
CLUSTAL X is a new windows interface for the widely-used progressive multiple sequence
alignment program CLUSTAL W. The new system is easy to use, providing an integrated …

Fast, scalable generation of high‐quality protein multiple sequence alignments using Clustal Omega

…, J Söding, JD Thompson, DG Higgins - Molecular systems …, 2011 - embopress.org
Multiple sequence alignments are fundamental to many sequence analysis methods. Most
alignments are computed using the progressive alignment heuristic. These methods are …

Clustal W and Clustal X version 2.0

…, R Lopez, JD Thompson, TJ Gibson, DG Higgins - …, 2007 - academic.oup.com
The Clustal W and Clustal X multiple sequence alignment programs have been completely
rewritten in C++. This will facilitate the further development of the alignment algorithms in the …

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix …

JD Thompson, DG Higgins, TJ Gibson - Nucleic acids research, 1994 - academic.oup.com
The sensitivity of the commonly used progressive multiple sequence alignment method has
been greatly improved for the alignment of divergent protein sequences. Firstly, individual …

Multiple sequence alignment with the Clustal series of programs

…, T Koike, R Lopez, TJ Gibson, DG Higgins… - Nucleic acids …, 2003 - academic.oup.com
The Clustal series of programs are widely used in molecular biology for the multiple alignment
of both nucleic acid and protein sequences and for preparing phylogenetic trees. The …

[22] Using CLUSTAL for multiple sequence alignments

DG Higgins, JD Thompson, TJ Gibson - Methods in enzymology, 1996 - Elsevier
We have tested CLUSTAL W in a wide variety of situations, and it is capable of handling some
very difficult protein alignment problems. If the data set consists of enough closely related …